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KMID : 0376119920190020229
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Medical Journal of the Red Cross Hospital
1992 Volume.19 No. 2 p.229 ~ p.236
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Demonstration of Immune complex in the Tissures of Autopsied Hemorrhagic Fever with Renal Syndrome Patients
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Abstract
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1) The immune complexes were observed in Hemorrhagic fever with renal syndrome(HFRS) patient's lungs and kidneys but not observed in normal human lungs and kidney tissues.
2) The immune complexes observed in the lungs of HFRS patients were different from kidneys of the same patient in morphology and distribution. In lungs, complexes were accumulated in some tissue regions such as bronchioles. In kidneys, they were
existed to amorphous clusters in all over the tissues.
3) These complexes were commonly observed in the lungs and kidneys of HFRS patients after polyvalent and anti-IgG, anti-complement C3 treatment, but not with anti-IgM and anti-IgA. Their fluorescent intensity was the strongest after treatment of
polyvalent, and anti-IgA. Their fluorescent intensity was the strongest after treatment of polyvalent, and anti-IgA. Anti-C3 was less than polyvalent but in case of immune complexes in lungs, C3 was the strongest and in order of polyvalent and
anti-IgG.
4) When these complexes were existed in lungs, their existence in kidneys were not certain. But when many immune complex clusters in kidneys were observed, they were not observed in lungs of same HFRS patient.
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